Treatment Refractory Depression, Only Happy On Pain Killers!


Q: just was wondering if anybody else feels very happy when they take pain killers? I know they very addicting and I can see why. It's a shame I have been suffering from depression for over 12 years and so I know all about this illness and meds and when you find a little something that makes you feel good for a little while your doc tells you not to take it. In the last year I notice that when I had physical problems and had to take pain killers they really make me happy for a few hours. I will admit it I will even try to find some to feel better. And of course I know I'm not supposed to do that but I get so mad that I do everything right to take care of myself like take meds, go to doc every freaking week,don't drink much any more and I still can,t get out of this hole. I'm even thinking about E.C.T. again{already had 16 treatments years ago} I just need to vent right now thanks for listening I'm going away tomorrow till the 15 of Jan. and I'm really going to miss this news group because there are so many people that here that feel like me. I just want to feel real again maybe get a job have a better life,this illness really really sucks big time,

A:Vicodin is the pain killer most often said to beat depression; I believe any codiene-derived substance can do the same. Here's the scivvy: For a week or ten days, using these in small amounts can make you feel quite good. Increase the dose or stay on them too long and it backfires: your depression will be worse than before. Sigmund Freud used cocaine (straight!) to treat meloncholics. It was considered a miracle drug till it's dark side (AND ADDICTIVE NATURE!) became known. As late as the 50s amphetemines with similar mental effects as cocaine were used in the treatment of severe depression because they didn't have much else to work with. (As a drug resistant depressive I have to laugh at that one.... they don't have much to work with now either!) I find opioid pain killers to have too many side effects to be very useful to me as antidepressants, but I have been prescribed two of them -- buprenorphine and morphine (slow-release) -- for depression in the past. They definitely did help, and rapidly. I did not develop tolerance. This apparently is the usual course of things when they are used to treat depression, according to pdocs I've talked to who've used the strategy. I didn't feel high or super-happy, but they brought me up into the light out of depression. They seem like a good idea if you can tolerate them and aren't predisposed to abuse them. Mary, you might want to try to find a psychopharmacologist who has experience using opioids for depression and get a consultation with him or her to see if he or she feels you're a good candidate for the treatment. A university medical center is probably the best place to find such a pdoc

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